MedChem Express Diversity Compound Libraries are available

Figure 1: Comparison of tanimoto coefficient between E brand and MCE: ranges from 0 to +1 (where +1 is the highest similarity)

High diversity

50K Diversity Library

• 50,000 compounds, 36,857 unique scaffolds (Bemis-Murcko)
• Each scaffold 1 to 7 compounds
• Average tanimoto coeffificient of 0.508

5K Scaffold Library

• 5,000 compounds, 5,000 unique scaffolds (Bemis-Murcko)
• Average tanimoto coeffificient of 0.28
• Maximum structural diversity

High hit probability

• All the compounds are drug-like, conforming to “Lipinski’s Rule of Five”

High reliability

• PAINS motifs or other inappropriate chemical structures removed
• NMR and HPLC validated to ensure high quality and purity (≥90%)

Convenient and time-saving

• Pre-plates of 10 mM in DMSO solutions

Excessive resupply with short delivery time